Patches vary in size. Skin coloring (pigmentation) and hair color can range from white to brown, and may be nearly the same as that of parents or siblings without albinism. Signs and symptoms of albinism involve skin, hair, and eye color and vision. However a girl who has purple eyes bo named Alexandria was treated as the reappearance of spirit people. Sometimes one eye has segments of two different colors. Skin. Generally, people with purple eyes have it along with other characteristic features like white skin, dark brown hair and so on. She was the first person has purple eyes according to the record. Alopecia areata is a chronic autoimmune disease in which the immune system attacks the hair follicles, causing hair loss, mainly from the scalp, though it can involve loss of eyebrows, eyelashes, beards, or any area of the body with hair. I recently read a strange article about this genetic mutation, better known as Alexandria's Genesis. Second is albinism. The usual color change is from your natural color to gray. Heterochromia is a variation in coloration.The term is most often used to describe color differences of the iris, but can also be applied to color variation of hair or skin.Heterochromia is determined by the production, delivery, and concentration of melanin (a pigment).It may be inherited, or caused by genetic mosaicism, chimerism, disease, or injury. Changes in your hair color can be a symptom of certain diseases, including osteoporosis, immune system and autoimmune disorders, Werner's syndrome, and vitiligo. Distinctive hair coloring (such as a patch of white hair or hair that prematurely turns gray) is … Other than these symptoms, individuals are thought to have pale, white skin that cannot be burned or tanned. Color change is usually associated with the number and activity of cells that produce pigment. The difference in color does not affect a person’s ability to see. People with this condition often have very pale blue eyes or different colored eyes, such as one blue eye and one brown eye. The most recognizable form of albinism results in white hair and very light-colored skin compared with siblings. White hair is also common in alopecia areata, an autoimmune skin condition that causes hair loss on the scalp, face and other parts of the body. Waardenburg syndrome is a group of rare genetic conditions characterised by at least some degree of congenital hearing loss and pigmentation deficiencies, which can include bright blue eyes (or one blue eye and one brown eye), a white forelock or patches of light skin. Alexandria Genesis is kind of a myth. Usually associated with women (though men are born with purple eyes as well), this disorder causes pale skin that is immune to tanning or sunburn, no body hair growth, no menstruation, high immunity, ideal body shape, and limited excretion of wastes. 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